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1

Modification of the furan ring of salvinorin A: Identification of a selective partial agonist at the kappa opioid receptor

Cécile Béguin, Katharine K. Duncan, Thomas A. Munro, Douglas M. Ho, Wei Xu, Lee-Yuan Liu-Chen, William A. Carlezon Jr., Bruce M. Cohen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 428 KB

english, 2009

2

Synthesis and in vitro pharmacological studies of new C(2) modified salvinorin A analogues

David Y.W. Lee, Vishnu V.R. Karnati, Minsheng He, Lee-Yuan Liu-Chen, Leelakrishna Kondaveti, Zhongze Ma, Yulin Wang, Yong Chen, Cecile Beguin, William A. Carlezon Jr., Bruce Cohen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 161 KB

english, 2005

3

Immunoelectron microscopic study of substance P-containing fibers in feline cerebral arteries

Lee-Yuan Liu-Chen, Theodore M. Liszczak, Joan C. King, Michael A. Moskowtiz

Journal:

Year:

1986

Language:

english

File:

PDF, 3.99 MB

english, 1986

4

Mephedrone (‘bath salt’) elicits conditioned place preference and dopamine-sensitive motor activation

Renata Lisek, Wei Xu, Ekaterina Yuvasheva, Yi-Ting Chiu, Allen B. Reitz, Lee-Yuan Liu-Chen, Scott M. Rawls

Journal:

Drug and Alcohol Dependence

Year:

2012

Language:

english

File:

PDF, 561 KB

english, 2012

5

Functional characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists

Xu, Wei, Wang, Xiaozhao, Tocker, Aaron M., Huang, Peng, Reith, Maarten E.A., Liu-Chen, Lee-Yuan, Smith, III, Amos B, Kortagere, Sandhya

Journal:

ACS Chemical Neuroscience

Year:

2016

Language:

english

File:

PDF, 2.36 MB

english, 2016

6

Biased signaling agonist of Dopamine D3 receptor induces receptor internalization independent of β-Arrestin recruitment

Xu, Wei, Reith, Maarten E.A., Chen, Lee-Yuan Liu, Kortagere, Sandhya

Journal:

Pharmacological Research

Year:

2019

Language:

english

File:

PDF, 1.82 MB

english, 2019

7

Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat μ opioid receptor

Yi-Feng Lu, Heng Xu, Lee-Yuan Liu-Chen, Chongguang Chen, John S. Partilla, George A. Brine, F. Ivy Carroll, Kenner C. Rice, Josephine Lai, Frank Porreca, Wolfgang Sadee, Richard B. Rothman

Journal:

Year:

1998

Language:

english

File:

PDF, 171 KB

english, 1998

8

Dual ultrastructural localization of μ-opiate receptors and substance p in the dorsal horn

Sue A. Aicher, Sarita Sharma, Peter Y. Cheng, Lee-Yuan Liu-Chen, Virginia M. Pickel

Journal:

Year:

2000

Language:

english

File:

PDF, 571 KB

english, 2000

9

Co-localization of retrogradely transported wheat germ agglutinin and the putative neurotransmitter substance P within trigeminal ganglion cells projecting to cat middle cerebral artery

Lee-Yuan Liu-Chen, Steven A. Gillespie, Thorkild V. Norregaard, Dr. Michael A. Moskowitz

Journal:

The Journal of Comparative Neurology

Year:

1984

Language:

english

File:

PDF, 652 KB

english, 1984

10

Butorphanol dependence increases hippocampal κ-opioid receptor gene expression

Sachiko Tanaka, Lir-Wan Fan, Lu-Tai Tien, Younjoo Park, Lee-Yuan Liu-Chen, Robin William Rockhold, Ing Kang Ho

Journal:

Journal of Neuroscience Research

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

11

Effects of acute agonist treatment on subcellular distribution of κ opioid receptor in rat spinal cord

Yulin Wang, Wei Xu, Peng Huang, Charles Chavkin, Elisabeth J. Van Bockstaele, Lee-Yuan Liu-Chen

Journal:

Journal of Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 668 KB

english, 2009

12

New neoclerodane diterpenoids isolated from the leaves of Salvia divinorum and their binding affinities for human κ opioid receptors

David Y.W. Lee, Zhongze Ma, Lee-Yuan Liu-Chen, Yulin Wang, Yong Chen, William A. Carlezon Jr., Bruce Cohen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 217 KB

english, 2005

13

Standard protecting groups create potent and selective κ opioids: Salvinorin B alkoxymethyl ethers

Thomas A. Munro, Katharine K. Duncan, Wei Xu, Yulin Wang, Lee-Yuan Liu-Chen, William A. Carlezon Jr., Bruce M. Cohen, Cécile Béguin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 238 KB

english, 2008

14

Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors

Zhongze Ma, Wei Xu, Lee-Yuan Liu-Chen, David Y.W. Lee

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 200 KB

english, 2008

15

Synthesis and in vitro pharmacological evaluation of salvinorin A analogues modified at C(2)

Cécile Béguin, Michele R. Richards, Yulin Wang, Yong Chen, Lee-Yuan Liu-Chen, Zhongze Ma, David Y.W. Lee, William A. Carlezon Jr., Bruce M. Cohen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 264 KB

english, 2005

16

Synthesis and in vitro evaluation of salvinorin A analogues: Effect of configuration at C(2) and substitution at C(18)

Cécile Béguin, Michele R. Richards, Jian-Guo Li, Yulin Wang, Wei Xu, Lee-Yuan Liu-Chen, William A. Carlezon Jr., Bruce M. Cohen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 197 KB

english, 2006

17

Corrigendum to “Synthesis and in vitro pharmacological studies of new C(4) modified salvinorin A analogues” [Bioorg. Med. Chem. Lett. 16 (2006) 5498–5502]

David Y.W. Lee, Minsheng He, Lee-Yuan Liu-Chen, Yulin Wang, Jian-Guo Li, Wei Xu, Zhongze Ma, William A. Carlezon Jr., Bruce Cohen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 67 KB

english, 2008

18

Corrigendum to “Synthesis and in vitro evaluation of salvinorin A analogues: Effect of configuration at C(2) and substitution at C(18)” [Bioorg. Med. Chem. Lett. 16 (2006) 4679–4685]

Cécile Béguin, Michele R. Richards, Jian-Guo Li, Yulin Wang, Wei Xu, Lee-Yuan Liu-Chen, William A. Carlezon Jr., Bruce M. Cohen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 112 KB

english, 2008

19

Synthesis and biological evaluation of C-12 triazole and oxadiazole analogs of salvinorin A

Lu Yang, Wei Xu, Feng Chen, Lee-Yuan Liu-Chen, Zhongze Ma, David Y.W. Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 316 KB

english, 2009

20

Synthesis and biological evaluation of C-2 halogenated analogs of salvinorin A

David Y.W. Lee, Lu Yang, Wei Xu, Gang Deng, Lin Guo, Lee-Yuan Liu-Chen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 358 KB

english, 2010

21

Thermal degradation products derived from the smoke of Salvia divinorum leaves

Zhongze Ma, Gang Deng, Ronghua Dai, Wei Xu, Lee-Yuan Liu-Chen, David Y.W. Lee

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010

22

Use of a μ-antisense oligodeoxynucleotide as a μ opioid receptor noncompetitive antagonist in vivo

Xiao-Hong Chen, Lee-Yuan Liu-Chen, Ronald J. Tallarida, Ellen B. Geller, J. Kim de Riel, Martin W. Adler

Journal:

Neurochemical Research

Year:

1996

Language:

english

File:

PDF, 602 KB

english, 1996

23

Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues

David Y.W. Lee, Minsheng He, Leelakrishna Kondaveti, Lee-Yuan Liu-Chen, Zhongze Ma, Yulin Wang, Yong Chen, Jian-Guo Li, Cecile Beguin, William A. Carlezon Jr., Bruce Cohen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 125 KB

english, 2005

24

Synthesis and in vitro pharmacological studies of new C(4)-modified salvinorin A analogues

David Y.W. Lee, Minsheng He, Lee-Yuan Liu-Chen, Yulin Wang, Jian-Guo Li, Wei Xu, Zhongze Ma, William A. Carlezon Jr., Bruce Cohen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

25

Intracerebroventricular treatment with an antisense oligodeoxynucleotide to κ-opioid receptors inhibited κ-agonist-induced analgesia in rats

Jill U. Adams, Xiaohong Chen, J. Kim DeRiel, Martin W. Adler, Lee-Yuan Liu-Chen

Journal:

Year:

1994

Language:

english

File:

PDF, 392 KB

english, 1994

26

Antisense oligodeoxynucleotides against μ- or κ-opioid receptors block agonist-induced body temperature changes in rats

Xiao-Hong Chen, Ellen B. Geller, J. Kim de Riel, Lee-Yuan Liu-Chen, Martin W. Adler

Journal:

Year:

1995

Language:

english

File:

PDF, 390 KB

english, 1995

27

Cholesterol reduction by methyl-β-cyclodextrin attenuates the delta opioid receptor-mediated signaling in neuronal cells but enhances it in non-neuronal cells

Peng Huang, Wei Xu, Su-In Yoon, Chongguang Chen, Parkson Lee-Gau Chong, Lee-Yuan Liu-Chen

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.18 MB

english, 2007

28

Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues

Cécile Béguin, Justin Potuzak, Wei Xu, Lee-Yuan Liu-Chen, John M. Streicher, Chad E. Groer, Laura M. Bohn, William A. Carlezon Jr., Bruce M. Cohen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 642 KB

english, 2012

29

Heterodimerization and cross-desensitization between the μ-opioid receptor and the chemokine CCR5 receptor

Chongguang Chen, Jin Li, George Bot, Imre Szabo, Thomas J. Rogers, Lee-Yuan Liu-Chen

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 649 KB

english, 2004

30

Effects of mu, kappa or delta opioids administered by pellet or pump on oral Salmonella infection and gastrointestinal transit

Pu Feng, Rahil T. Rahim, Alan Cowan, Lee-Yuan Liu-Chen, Xiaohui Peng, John Gaughan, Joseph J. Meissler Jr., Martin W. Adler, Toby K. Eisenstein

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 413 KB

english, 2006

31

Regulator of G protein signaling proteins differentially modulate signaling of μ and δ opioid receptors

Zhihua Xie, Zhisong Li, Lei Guo, Caiying Ye, Juan Li, Xiaoli Yu, Huifen Yang, Yulin Wang, Chongguang Chen, Dechang Zhang, Lee-Yuan Liu-Chen

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 524 KB

english, 2007

32

Possible mechanism of hypothermia induced by intracerebroventricular injection of orphanin FQ/nociceptin

Xiaohong Chen, Daniel B McClatchy, Ellen B Geller, Lee-Yuan Liu-Chen, Ronald J Tallarida, Martin W Adler

Journal:

Year:

2001

Language:

english

File:

PDF, 219 KB

english, 2001

33

Dual ultrastructural immunocytochemical labeling of μ and δ opioid receptors in the superficial layers of the rat cervical spinal cord

Peter Y Cheng, Lee-Yuan Liu-Chen, Virginia M Pickel

Journal:

Year:

1997

Language:

english

File:

PDF, 5.81 MB

english, 1997

34

Apparent thermodynamic parameters of ligand binding to the cloned rat μ-opioid receptor

Jian-Guo Li, Robert B Raffa, Peter Cheung, Tsang-Bin Tzeng, Lee-Yuan Liu-Chen

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 225 KB

english, 1998

35

Nucleoside diphosphate kinase associated with membranes modulates μ-opioid receptor-mediated [35S]GTPγS binding and agonist binding to μ-opioid receptor

Dechang Zhang, Jian-Guo Li, Chongguang Chen, Lee-Yuan Liu-Chen

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 262 KB

english, 1999

36

Characterization of κ-opioid receptor transcripts expressed by T cells and macrophages

Candido Alicea, Stanley M. Belkowski, Judith K. Sliker, Jinmin Zhu, Lee-Yuan Liu-Chen, Toby K. Eisenstein, Martin W. Adler, Thomas J. Rogers

Journal:

Journal of Neuroimmunology

Year:

1998

Language:

english

File:

PDF, 645 KB

english, 1998

37

Substance P-like immunoreactivity in rat forebrain leptomeninges and cerebral vessels originates from the trigeminal but not sympathetic ganglia

Kiyoshi Saito, Lee-Yuan Liu-Chen, Michael A. Moskowitz

Journal:

Year:

1987

Language:

english

File:

PDF, 1.13 MB

english, 1987

38

Autoradiographic study of irreversible binding of [3H]β-funaltrexamine to opioid receptors in the rat forebrain: comparison with μ and δ receptor distribution

Lee-Yuan Liu-Chen, Shuixing Li, Michael E. Lewis

Journal:

Year:

1991

Language:

english

File:

PDF, 854 KB

english, 1991

39

[3H]β-funaltrexamine binds covalently to brain opioid receptors

S. William Tam, Victor J. Nickolson, Lee-Yuan Liu-Chen

Journal:

European Journal of Pharmacology

Year:

1985

Language:

english

File:

PDF, 130 KB

english, 1985

40

Effects of intracerebroventricular β-funaltrexamine on μ and δ opioid receptors in the rat: dichotomy between binding and antinociception

Lee-Yuan Liu-Chen, Shuixing Li, Helen Wheeler-Aceto, Alan Cowan

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.17 MB

english, 1991

41

An antisense oligodeoxynucleotide to μ-opioid receptors inhibits μ-opioid receptor agonist-induced analgesia in rats

Xiao-Hong Chen, Jill U. Adams, Ellen B. Geller, J.Kim DeRiel, Martin W. Adler, Lee-Yuan Liu-Chen

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 415 KB

english, 1995

42

The region in the μ opioid receptor conferring selectivity for sufentanil over the δ receptor is different from that over the κ receptor

Jinmin Zhu, Ji-Chun Xue, Ping-Yee Law, Patricia A. Claude, Lai-Yi Luo, Jinling Yin, Chongguang Chen, Lee-Yuan Liu-Chen

Journal:

Year:

1996

Language:

english

File:

PDF, 475 KB

english, 1996

43

Brain region-specific N-glycosylation and lipid rafts association of the rat mu opioid receptor

Peng Huang, Chongguang Chen, Wei Xu, Su-In Yoon, Ellen M. Unterwald, John E. Pintar, Yulin Wang, Parkson Lee-Gau Chong, Lee-Yuan Liu-Chen

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 690 KB

english, 2008

44

Agonist-induced regulation and trafficking of κ opioid receptors

Lee-Yuan Liu-Chen

Journal:

Year:

2004

Language:

english

File:

PDF, 323 KB

english, 2004

45

Dynorphin peptides differentially regulate the human κ opioid receptor

Yong Chen, Chongguang Chen, Lee-Yuan Liu-Chen

Journal:

Year:

2007

Language:

english

File:

PDF, 694 KB

english, 2007

46

In vivo trafficking of endogenous opioid receptors

Yulin Wang, Elisabeth J. Van Bockstaele, Lee-Yuan Liu-Chen

Journal:

Year:

2008

Language:

english

File:

PDF, 396 KB

english, 2008

47

Sex differences in kappa opioid pharmacology

Khampaseuth Rasakham, Lee-Yuan Liu-Chen

Journal:

Year:

2011

Language:

english

File:

PDF, 330 KB

english, 2011

48

Hyperlocomotion and paw tremors are two highly quantifiable signs of SR141716-precipitated withdrawal from delta9-tetrahydrocannabinol in C57BL/6 mice

Peng Huang, Lee-Yuan Liu-Chen, Ellen M. Unterwald, Alan Cowan

Journal:

Neuroscience Letters

Year:

2009

Language:

english

File:

PDF, 415 KB

english, 2009

49

Anxiety-like effects of SR141716-precipitated delta9-tetrahydrocannabinol withdrawal in mice in the elevated plus-maze

Peng Huang, Lee-Yuan Liu-Chen, Lynn G. Kirby

Journal:

Neuroscience Letters

Year:

2010

Language:

english

File:

PDF, 411 KB

english, 2010

50

Young and older good learners have higher levels of brain nicotinic receptor binding

Diana S. Woodruff-Pak, Melissa A. Lehr, Jian-Guo Li, Lee-Yuan Liu-Chen

Journal:

Neurobiology of Aging

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010